A novel batch fabrication of micro parts using DNA pattern recognition

Masafumi Yasuda, Terutake Hayashi, Masaki Michihata, Yasuhiro Takaya

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)


We proposed a novel technique for self-assembly of micro parts by using DNA hybridization. As the demand for MEMS is growing, research on the self-assembly of micro parts is required to achieve fabrication of functional devices consisted of diverse micro parts. Our method has a unique characteristic where the selective assembly can be performed. At the targeted substrate region functionalized by single-stranded DNA, only components functionalized by the complementary one are assembled successfully. This is due to the complementary properties of DNA, which consists of four different bases (adenine (A), cytosine (C), guanine (G), and thymine (T)). A of one strand always pairs with a T of another, and so does C with G. The characteristic enables batch fabrication of diverse micro parts by using several kinds of DNA properly. Therefore, our method can be applied to the fabrication of MEMS. In this paper, in order to verify the feasibility of the automatic positioning using DNA hybridization, we performed a fundamental experiment for addressing polystyrene microspheres (1, 2, 6μm diameter) on the DNA patterned glass substrate.

Original languageEnglish
Title of host publicationEmerging Technology in Precision Engineering XIV
PublisherTrans Tech Publications Ltd
Number of pages6
ISBN (Print)9783037855096
Publication statusPublished - 2012
Externally publishedYes
Event14th International Conference on Precision Engineering, ICPE 2012 - Hyogo, Japan
Duration: Nov 8 2012Nov 10 2012

Publication series

NameKey Engineering Materials
ISSN (Print)1013-9826
ISSN (Electronic)1662-9795


Other14th International Conference on Precision Engineering, ICPE 2012

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering


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