TY - JOUR
T1 - A New Ligand for Europium(III) That Forms a Stable Fluorescent Complex in Aqueous Solution
AU - Horiguchi, Daikichi
AU - Katayama, Yoshiki
AU - Sasamoto, Kazumi
AU - Terasawa, Hideyuki
AU - Sato, Naofumi
AU - Mochizuki, M.
AU - Ohkura, Yosuke
PY - 1992
Y1 - 1992
N2 - A new macrocyclic ligand for Eu3 +, 24,30-diphenyl-8,19-(l,21:4,6:10,12:15,17-tetraetheno-8,9,19,20-tetrahydro-7AT,18^r-dibenzo[A,^][l,4,7,10,13,16]hexaazacyclooctadecine)diacetic acid (1), was synthesized and its fluorescence characteristics were examined, particularly to compare with 4,7-bis(chlorosulfophenyl)-l,10-phenanthroline-2,9-dicarboxylic acid (BCPDA) that has proved to be useful as a label in time-resolved fluoroimmunoassays. The complex of macrocycle 1 with Eu3+ was found to have a higher fluorescence intensity as well as a longer fluorescence lifetime than that of BCPDA.
AB - A new macrocyclic ligand for Eu3 +, 24,30-diphenyl-8,19-(l,21:4,6:10,12:15,17-tetraetheno-8,9,19,20-tetrahydro-7AT,18^r-dibenzo[A,^][l,4,7,10,13,16]hexaazacyclooctadecine)diacetic acid (1), was synthesized and its fluorescence characteristics were examined, particularly to compare with 4,7-bis(chlorosulfophenyl)-l,10-phenanthroline-2,9-dicarboxylic acid (BCPDA) that has proved to be useful as a label in time-resolved fluoroimmunoassays. The complex of macrocycle 1 with Eu3+ was found to have a higher fluorescence intensity as well as a longer fluorescence lifetime than that of BCPDA.
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U2 - 10.1248/cpb.40.3334
DO - 10.1248/cpb.40.3334
M3 - Article
AN - SCOPUS:0027083138
SN - 0009-2363
VL - 40
SP - 3334
EP - 3337
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
IS - 12
ER -