A new approach to asymmetric synthesis of β-amino alcohols by means of α-chirally protected amino alkyllithiums

Takahiro Tomoyasu; Katsuhiko Tomooka; Takeshi Nakai

doi:10.1055/s-1998-1891

A new approach to asymmetric synthesis of β-amino alcohols by means of α-chirally protected amino alkyllithiums

Takahiro Tomoyasu, Katsuhiko Tomooka, Takeshi Nakai

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

A new, general synthetic approach to enantiopure α-amino ketones and syn-β-amino alcohols is described which employs the doubly chiral N-protected α-amino alkyllithiums generated via Pearson's transmetalative protocol as the key synthetic intermediates.

Original language	English
Pages (from-to)	1147-1149
Number of pages	3
Journal	Synlett
Issue number	10
DOIs	https://doi.org/10.1055/s-1998-1891
Publication status	Published - Oct 1998
Externally published	Yes

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1055/s-1998-1891

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title = "A new approach to asymmetric synthesis of β-amino alcohols by means of α-chirally protected amino alkyllithiums",

abstract = "A new, general synthetic approach to enantiopure α-amino ketones and syn-β-amino alcohols is described which employs the doubly chiral N-protected α-amino alkyllithiums generated via Pearson's transmetalative protocol as the key synthetic intermediates.",

author = "Takahiro Tomoyasu and Katsuhiko Tomooka and Takeshi Nakai",

year = "1998",

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AU - Nakai, Takeshi

PY - 1998/10

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AB - A new, general synthetic approach to enantiopure α-amino ketones and syn-β-amino alcohols is described which employs the doubly chiral N-protected α-amino alkyllithiums generated via Pearson's transmetalative protocol as the key synthetic intermediates.

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A new approach to asymmetric synthesis of β-amino alcohols by means of α-chirally protected amino alkyllithiums

Abstract

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