A large-scale observational study to investigate the current status of diabetic complications and their prevention in Japan: Oral and dental findings at baseline -JDCP study 6-

Koji Inagaki, Takeshi Kikuchi, Toshihide Noguchi, Akio Mitani, Keiko Naruse, Tatsuaki Matsubara, Masamitsu Kawanami, Jun Negishi, Yasushi Furuichi, Eiji Nemoto, Satoru Yamada, Hiromasa Yoshie, Koichi Tabeta, Sachiyo Tomita, Atsushi Saito, Sayaka Katagiri, Yuichi Izumi, Hiroshi Nitta, Takanori Iwata, Yukihiro NumabeMatsuo Yamamoto, Nobuo Yoshinari, Tsuyoshi Fujita, Hidemi Kurihara, Fusanori Nishimura, Toshihiko Nagata, Hiromichi Yumoto, Toru Naito, Kazuyuki Noguchi, Koichi Ito, Shinya Murakami, Rimei Nishimura, Naoko Tajima

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The Japan Diabetes Complications and its Prevention (JDCP) prospective study was conducted to analyze the association between glycemic control and oral conditions in a large database of Japanese patients with diabetes. It included a total of 6,099 patients with diabetes (range, 40-75 years) who were treated as outpatients between 2007 and 2009. The mean number of teeth at baseline was 19.8 and women had fewer teeth than men in type 2 diabetes. Within the previous year, 17 % had lost teeth. At baseline, 32 % had experienced gingival swelling, 69 % brushed more than twice a day, 37 % used interdental devices, and 43 % received dental regular checkups. A multiple logistic regression analysis indicated that type 1 diabetic patients with HbAlc 7.0 % had a higher risk having fewer than 20 teeth (odds ratio [OR]: 2.38; 95 % confidence interval [CI]: 1.25-4.78), and type 2 diabetic patients with HbAlc 8.0 % also had a high risk having fewer than 20 teeth (OR: 1.16; 95 % CI: 1.00-1.34), after adjusting for 9 possible confounders. In conclusion, diabetic patients had a high risk of tooth loss and the poorer the glycemic control, the higher the risk of tooth loss.

Original languageEnglish
Pages (from-to)195-205
Number of pages11
JournalJournal of the Japan Diabetes Society
Volume63
Issue number4
DOIs
Publication statusPublished - 2020

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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