A fluorescent probe for detection of histone deacetylase activity based on aggregation-induced emission

Koushik Dhara, Yuichiro Hori, Reisuke Baba, Kazuya Kikuchi

Research output: Contribution to journalArticlepeer-review

64 Citations (Scopus)

Abstract

A tetraphenylethylene-derivative fluorescent probe for the one-step detection of histone deacetylases (HDAC) was developed. The deacetylation of the probe triggers electrostatic interaction between the molecules and automatically leads to fluorescence enhancement based on aggregation-induced emission (AIE).

Original languageEnglish
Pages (from-to)11534-11536
Number of pages3
JournalChemical Communications
Volume48
Issue number94
DOIs
Publication statusPublished - Oct 31 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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