A computational model of myocardial microcirculation including interstitial flow

Takao Shimayoshi; Yuta Yamamoto; Tetsuya Matsuda

doi:10.1109/EMBC.2017.8037653

A computational model of myocardial microcirculation including interstitial flow

Takao Shimayoshi, Yuta Yamamoto, Tetsuya Matsuda

Research Institute for Information Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

Contributions of interstitial fluid (ISF) flow within the myocardial microcirculation is not well understood despite its importance due to difficulties in measurements. For analysing a contribution of interstitial fluid flow within myocardial microcirculation, we developed a computational model of myocardial microcirculation by introducing convection by the ISF flow into an existing myocardial microcirculation model, and performed simulations with varied ISF flows in normal and hypoperfusion conditions. Simulation results show that the ISF flow has a contribution only with low capillary flow. This might suggest partial comensation of oxygen supply by the ISF flow under ischemic conditions.

Original language	English
Title of host publication	2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publication	Smarter Technology for a Healthier World, EMBC 2017 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	3668-3671
Number of pages	4
ISBN (Electronic)	9781509028092
DOIs	https://doi.org/10.1109/EMBC.2017.8037653
Publication status	Published - Sept 13 2017
Event	39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017 - Jeju Island, Korea, Republic of Duration: Jul 11 2017 → Jul 15 2017

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)	1557-170X

Other

Other	39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017
Country/Territory	Korea, Republic of
City	Jeju Island
Period	7/11/17 → 7/15/17

All Science Journal Classification (ASJC) codes

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Access to Document

10.1109/EMBC.2017.8037653

Cite this

Shimayoshi, T., Yamamoto, Y., & Matsuda, T. (2017). A computational model of myocardial microcirculation including interstitial flow. In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings (pp. 3668-3671). Article 8037653 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2017.8037653

A computational model of myocardial microcirculation including interstitial flow. / Shimayoshi, Takao; Yamamoto, Yuta; Matsuda, Tetsuya.
2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. p. 3668-3671 8037653 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Shimayoshi, T, Yamamoto, Y & Matsuda, T 2017, A computational model of myocardial microcirculation including interstitial flow. in 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings., 8037653, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers Inc., pp. 3668-3671, 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2017, Jeju Island, Korea, Republic of, 7/11/17. https://doi.org/10.1109/EMBC.2017.8037653

Shimayoshi T, Yamamoto Y, Matsuda T. A computational model of myocardial microcirculation including interstitial flow. In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2017. p. 3668-3671. 8037653. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2017.8037653

Shimayoshi, Takao ; Yamamoto, Yuta ; Matsuda, Tetsuya. / A computational model of myocardial microcirculation including interstitial flow. 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Smarter Technology for a Healthier World, EMBC 2017 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2017. pp. 3668-3671 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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AB - Contributions of interstitial fluid (ISF) flow within the myocardial microcirculation is not well understood despite its importance due to difficulties in measurements. For analysing a contribution of interstitial fluid flow within myocardial microcirculation, we developed a computational model of myocardial microcirculation by introducing convection by the ISF flow into an existing myocardial microcirculation model, and performed simulations with varied ISF flows in normal and hypoperfusion conditions. Simulation results show that the ISF flow has a contribution only with low capillary flow. This might suggest partial comensation of oxygen supply by the ISF flow under ischemic conditions.

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A computational model of myocardial microcirculation including interstitial flow

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