A comprehensive evaluation of the virulence of oral flora

Yoshihisa Yamashita, Toru Takeshita

Research output: Chapter in Book/Report/Conference proceedingChapter


The oral cavity is inhabited by more than 700 species of commensal bacteria. Several have been identified as pathogens of oral diseases, dental caries, and periodontal diseases. However, the lack of information concerning the interaction between pathogens and the remaining commensal bacteria has made it difficult to understand the precise etiologies of oral diseases. We need to identify the comprehensive species found in individual oral flora and compare these results with corresponding oral health conditions. In this chapter, the authors delineate the previous attempts to identify oral commensal bacterial flora and discuss the potential capability of modern molecular genetic technologies such as terminal restriction fragment length polymorphism, DNA microarray and pyrosequencing analyses utilizing bioinformatics.

Original languageEnglish
Title of host publicationInformatics in Oral Medicine
Subtitle of host publicationAdvanced Techniques in Clinical and Diagnostic Technologies
PublisherIGI Global
Number of pages17
ISBN (Print)9781605667331
Publication statusPublished - 2010

All Science Journal Classification (ASJC) codes

  • Health Professions(all)


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