A case of unresectable hilar bile duct cancer responding to chemo-radiotherapy by gemcitabine

Naohiko Kohya; Kazuyoshi Hashiguchi; Tomomi Yakabe; Atsushi Miyoshi; Takao Ohtsuka; Kenji Kitahara; Kohji Miyazaki

A case of unresectable hilar bile duct cancer responding to chemo-radiotherapy by gemcitabine

Naohiko Kohya, Kazuyoshi Hashiguchi, Tomomi Yakabe, Atsushi Miyoshi, Takao Ohtsuka, Kenji Kitahara, Kohji Miyazaki

Department of Endoscopic Diagnostics Therapeutics

Research output: Contribution to journal › Article › peer-review

Abstract

A 66-year-old woman was admitted to our hospital because of general fatigue and icterus. PTC findings showed irregular stenosis of hilar bile duct. Abdominal CT scan showed a dilatation of the intra-hepatic bile duct and a tumor around hilar bile duct. We diagnosed it as hilar bile duct carcinoma, and although we operated it was unresectable because of the metastasis of a para-aorta lymph node and duodenal invasion. We started chemo-radiotherapy with a total dose of 45 Gy and gemcitabine. The tumor and para-aorta lymph node were remarkably decreased, and tumor marker CA19-9 was also decreased to within the normal range. The patient had a peritoneal dissemination 10 months after the chemo-radiotherapy and survived 20 months.

Original language	English
Pages (from-to)	1753-1755
Number of pages	3
Journal	Japanese Journal of Cancer and Chemotherapy
Volume	36
Issue number	10
Publication status	Published - Oct 2009

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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abstract = "A 66-year-old woman was admitted to our hospital because of general fatigue and icterus. PTC findings showed irregular stenosis of hilar bile duct. Abdominal CT scan showed a dilatation of the intra-hepatic bile duct and a tumor around hilar bile duct. We diagnosed it as hilar bile duct carcinoma, and although we operated it was unresectable because of the metastasis of a para-aorta lymph node and duodenal invasion. We started chemo-radiotherapy with a total dose of 45 Gy and gemcitabine. The tumor and para-aorta lymph node were remarkably decreased, and tumor marker CA19-9 was also decreased to within the normal range. The patient had a peritoneal dissemination 10 months after the chemo-radiotherapy and survived 20 months.",

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AU - Kohya, Naohiko

AU - Hashiguchi, Kazuyoshi

AU - Yakabe, Tomomi

AU - Miyoshi, Atsushi

AU - Ohtsuka, Takao

AU - Kitahara, Kenji

AU - Miyazaki, Kohji

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N2 - A 66-year-old woman was admitted to our hospital because of general fatigue and icterus. PTC findings showed irregular stenosis of hilar bile duct. Abdominal CT scan showed a dilatation of the intra-hepatic bile duct and a tumor around hilar bile duct. We diagnosed it as hilar bile duct carcinoma, and although we operated it was unresectable because of the metastasis of a para-aorta lymph node and duodenal invasion. We started chemo-radiotherapy with a total dose of 45 Gy and gemcitabine. The tumor and para-aorta lymph node were remarkably decreased, and tumor marker CA19-9 was also decreased to within the normal range. The patient had a peritoneal dissemination 10 months after the chemo-radiotherapy and survived 20 months.

AB - A 66-year-old woman was admitted to our hospital because of general fatigue and icterus. PTC findings showed irregular stenosis of hilar bile duct. Abdominal CT scan showed a dilatation of the intra-hepatic bile duct and a tumor around hilar bile duct. We diagnosed it as hilar bile duct carcinoma, and although we operated it was unresectable because of the metastasis of a para-aorta lymph node and duodenal invasion. We started chemo-radiotherapy with a total dose of 45 Gy and gemcitabine. The tumor and para-aorta lymph node were remarkably decreased, and tumor marker CA19-9 was also decreased to within the normal range. The patient had a peritoneal dissemination 10 months after the chemo-radiotherapy and survived 20 months.

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A case of unresectable hilar bile duct cancer responding to chemo-radiotherapy by gemcitabine

Abstract

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