A case of successful treatment using "wrapping therapy" for huge hepatocellular carcinoma

Terumasa Yamada, Y. Sasaki, Kentaro Kishi, Shingo Noura, K. Takachi, Hidetoshi Eguchi, Isao Miyashiro, Masayuki Ohue, Masahiko Yano, Hiroaki Ohigashi, Osamu Ishikawa, Shingi Imaoka

Research output: Contribution to journalArticlepeer-review


This case is about a male in his 50's. In May 2004, he consulted a nearby doctor with abdominal pain and was pointed out a huge mass in the liver. He was diagnosed as hepatocellular carcinoma over 10 cm in diameter with chronic hepatitis type B. Because the tumor concurred with intra-hepatic metastasis along with lymph node metastasis, we planned transhepatic arterial embolization (TAE) as a first choice of treatment and performed twice. However, because of the tail inside part of the tumor was supplied from the gastroduodenal artery (GDA) and right gastroepiploic artery (RGEA) which were nutrient arteries, an effective TAE was impossible. The enhancement lesion that seemed viable was shown by enhanced CT. Therefore, a wrapping therapy (surgical decollateralization+silicon membrane sheeting) was performed under laparotomy for the purpose of cutting off blood supply to the part of the viable lesion in August of the same year. The tail inside part of the tumor that seemed viable fell into necrosis by wrapping alone, and the serum PIVKA-II level decreased within normal limit. As of ten months after the treatment, the patient is still alive without aggravation.

Original languageEnglish
Pages (from-to)1801-1804
Number of pages4
JournalGan to kagaku ryoho. Cancer & chemotherapy
Issue number11
Publication statusPublished - Oct 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine


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