A Case of Primary Cutaneous B-cell Lymphoma

Yoshiyuki Murakami, Kazunori Urabe, Masutaka Furue, Koji Irie

Research output: Contribution to journalArticlepeer-review


We herein report the ease of a 75-year-old Japanese woman who presented with multiple cutaneous nodules on her trunk and left upper limb and thus was diagnosed to have primary cutaneous B-cell lymphoma (pCBCL). We could not detect any extra-cutaneous lesions in the patient. Histologically, the nodule showed nonepidermotropic diffuse dermal infiltrates, which mainly consisted of large abnormal lymphoid cells. Imrnunohistochernically, these neoplastic cells expressed CD19, CD20, x type slg. An immunoglobulin gene rearrangement of the neoplastic cells of the cutaneous nodule was shown by a Southern blot analysis. Based on these clinical and laboratory findings, she was diagnosed to have diffuse large cell type pCBCL. She was treated by THP-COP chemotherapy and 30 Gy of local radiotherapy with an electron beam. No relapse was noticed at 14 months after the initial treatment.

Original languageEnglish
Pages (from-to)471-475
Number of pages5
JournalNishinihon Journal of Dermatology
Issue number4
Publication statusPublished - 1998

All Science Journal Classification (ASJC) codes

  • Dermatology


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