A case of MALT lymphoma with gammaglobulinemia and systemic lymph node swelling

Ruriko Kohno; Hiroshi Yoshikawa; Ri Ichiro Kohno; Kimiko Ishida; Toshinori Murata; Yoh Ichi Kawano; Tatsuro Ishibashi; Kennosuke Karube; Kazuya Shimoda

A case of MALT lymphoma with gammaglobulinemia and systemic lymph node swelling

Ruriko Kohno, Hiroshi Yoshikawa, Ri Ichiro Kohno, Kimiko Ishida, Toshinori Murata, Yoh Ichi Kawano, Tatsuro Ishibashi, Kennosuke Karube, Kazuya Shimoda

Kyushu University Hospital

Research output: Contribution to journal › Article › peer-review

Abstract

A 59-year-old male presented with impaired visual acuity in both eyes. He had been diagnosed with bilateral orbital lymphoid hyperplasia 23 years before. He had received radiation to his left orbit 16 years before. Biopsy of right orbital tumor 4 years before had led to the diagnosis of mucosa-associated lymphoid tissue (MALT) lymphoma, followed by radiation and systemic chemotherapy. His corrected visual acuity was 0.1 right and 0.5 left. He showed progression of orbital tumor, systemic lymphnode swelling and gammaglobulinemia. He had also gastric tumor, which was diagnosed as MALT lymphoma. Biopsy of cervical lymphnode showed no clonality of Ig gene. Systemic chemotherapy led to partial regression of lymphoma and to decreased serum level of immunoglobulin. MALT lymphoma in the present case appeared to be of orbital origin.

Original language	English
Pages (from-to)	1855-1860
Number of pages	6
Journal	Japanese Journal of Clinical Ophthalmology
Volume	59
Issue number	12
Publication status	Published - Dec 2005

All Science Journal Classification (ASJC) codes

Ophthalmology

Cite this

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title = "A case of MALT lymphoma with gammaglobulinemia and systemic lymph node swelling",

abstract = "A 59-year-old male presented with impaired visual acuity in both eyes. He had been diagnosed with bilateral orbital lymphoid hyperplasia 23 years before. He had received radiation to his left orbit 16 years before. Biopsy of right orbital tumor 4 years before had led to the diagnosis of mucosa-associated lymphoid tissue (MALT) lymphoma, followed by radiation and systemic chemotherapy. His corrected visual acuity was 0.1 right and 0.5 left. He showed progression of orbital tumor, systemic lymphnode swelling and gammaglobulinemia. He had also gastric tumor, which was diagnosed as MALT lymphoma. Biopsy of cervical lymphnode showed no clonality of Ig gene. Systemic chemotherapy led to partial regression of lymphoma and to decreased serum level of immunoglobulin. MALT lymphoma in the present case appeared to be of orbital origin.",

author = "Ruriko Kohno and Hiroshi Yoshikawa and Kohno, {Ri Ichiro} and Kimiko Ishida and Toshinori Murata and Kawano, {Yoh Ichi} and Tatsuro Ishibashi and Kennosuke Karube and Kazuya Shimoda",

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language = "English",

volume = "59",

pages = "1855--1860",

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T1 - A case of MALT lymphoma with gammaglobulinemia and systemic lymph node swelling

AU - Kohno, Ruriko

AU - Yoshikawa, Hiroshi

AU - Kohno, Ri Ichiro

AU - Ishida, Kimiko

AU - Murata, Toshinori

AU - Kawano, Yoh Ichi

AU - Ishibashi, Tatsuro

AU - Karube, Kennosuke

AU - Shimoda, Kazuya

PY - 2005/12

Y1 - 2005/12

N2 - A 59-year-old male presented with impaired visual acuity in both eyes. He had been diagnosed with bilateral orbital lymphoid hyperplasia 23 years before. He had received radiation to his left orbit 16 years before. Biopsy of right orbital tumor 4 years before had led to the diagnosis of mucosa-associated lymphoid tissue (MALT) lymphoma, followed by radiation and systemic chemotherapy. His corrected visual acuity was 0.1 right and 0.5 left. He showed progression of orbital tumor, systemic lymphnode swelling and gammaglobulinemia. He had also gastric tumor, which was diagnosed as MALT lymphoma. Biopsy of cervical lymphnode showed no clonality of Ig gene. Systemic chemotherapy led to partial regression of lymphoma and to decreased serum level of immunoglobulin. MALT lymphoma in the present case appeared to be of orbital origin.

AB - A 59-year-old male presented with impaired visual acuity in both eyes. He had been diagnosed with bilateral orbital lymphoid hyperplasia 23 years before. He had received radiation to his left orbit 16 years before. Biopsy of right orbital tumor 4 years before had led to the diagnosis of mucosa-associated lymphoid tissue (MALT) lymphoma, followed by radiation and systemic chemotherapy. His corrected visual acuity was 0.1 right and 0.5 left. He showed progression of orbital tumor, systemic lymphnode swelling and gammaglobulinemia. He had also gastric tumor, which was diagnosed as MALT lymphoma. Biopsy of cervical lymphnode showed no clonality of Ig gene. Systemic chemotherapy led to partial regression of lymphoma and to decreased serum level of immunoglobulin. MALT lymphoma in the present case appeared to be of orbital origin.

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A case of MALT lymphoma with gammaglobulinemia and systemic lymph node swelling

Abstract

All Science Journal Classification (ASJC) codes

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