Abstract
A 68-year-old man was introduced to our hospital with right lower abdominal pain. Endoscopic examination and abdominal CT revealed gastric cancer with liver metastasis. We started chemotherapy using S-1 (120 mg/body/day), orally administered for 2 weeks followed by a 2-week rest period, and docetaxel (35 mg/m2), administered intravenously on day 1 and 15 as 1 course. After 4 courses of chemotherapy, the liver tumor reduced markedly and no new cancerous region was found by examination; therefore total gastrectomy and partial hepatectomy were performed. Histological examination showed an undifferentiated adenocarcinoma remaining as Grade 1b in the resected stomach. A resected specimen of the liver showed necrotic tissue without any cancer cells. This case suggests that S-1/docetaxel chemotherapy may reduce the stage of unresectable liver metastasis from gastric cancer and make a curative operation possible.
| Original language | English |
|---|---|
| Pages (from-to) | 1093-1097 |
| Number of pages | 5 |
| Journal | Japanese Journal of Cancer and Chemotherapy |
| Volume | 40 |
| Issue number | 8 |
| Publication status | Published - Aug 2013 |
All Science Journal Classification (ASJC) codes
- Oncology
- Cancer Research
