A case of interstitial pneumonia with smoldering adult T-cell leukemia

Saiko Ogata, Naoki Hamada, Takashige Maeyama, Koichi Takayama, Hiromasa Inoue, Yoichi Nakanishi

Research output: Contribution to journalArticlepeer-review


A 66-year-old woman was admitted because of dry cough and dyspnea. Computed tomography showed ground-glass opacities and traction bronchiectasis in both lung fields. Then, ATL cells appeared in her peripheral blood, and the number of lymphocytes in BALF increased. Inverse PCR for HTLV-1 clonality of the peripheral blood revealed a polyclonal pattern, and she was given a diagnosis of smoldering adult T-cell leukemia. Using BALF flow cytometry, both CD4- and CD25-positive cells accounted for only 0.8%. Secondary interstitial pneumonia was diagnosed and we started therapy with prednisolone and cyclophosphamide. BALF flow cytometry may be useful in the differential diagnosis of ATL lung lesions.

Original languageEnglish
Pages (from-to)293-297
Number of pages5
JournalNihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
Issue number4
Publication statusPublished - Apr 2010

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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