A case of hypopharyngeal ulceration due to cytomegarovirus infection

Marie Kubota, Takahiro Wakasaki, Takenao Mihara, Junichi Fukushima

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Cytomegalovirus (CMV) is a common opportunistic infection in immunosuppressive patients. One of the organs often involved is the gastrointestinal tract, but the pharynx, especially hypopharyngeal involvement, is rare. In this report, we present a case of a 61-year-old male compromised host, admitted to the hospital for the treatment of dermatomyositis, who presented with hypopharyngeal ulceration due to cytomegalovirus infection. Multiple deep ulcerative lesions with thick belaque, or with a protruding bony edge were observed in the adjacent areas in/around the hypopharynx, which repeatedly demonstrated exacerbation and remission in a relatively short period. The lesions developed acute bleeding and required emergency operative hemostasis. The ulcerations completely disappeared after the treatment with gancyclovir. We reviewed our case as well as other cases reported so far, and extracted the points we should be aware of when we encounter a case of hypopharyngeal ulceration based on cytomegalovirus infection; 1. acute bleeding, 2. paralysis of the vocal cords and subsequent breathing difficulty, 3. pharyngeal perforation.

Original languageEnglish
Pages (from-to)1258-1263
Number of pages6
JournalJournal of Otolaryngology of Japan
Issue number10
Publication statusPublished - 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology


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