A case of genital folliculosebaceous cystic hamartoma with an unique aggregated manifestation

Manabu Hamada, Hiromaro Kiryu, Emiko Satoh, Yoichi Moroi, Kazunori Urabe, Masutaka Furue

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17 Citations (Scopus)


Folliculosebaceous cystic hamartoma (FCH) is a recently recognized cutaneous hamartoma composed of follicular, sebaceous and mesenchymal components, and usually occurring on the head and neck. We describe herein a case of FCH with an unique aggregated manifestation in a genital lesion. The patient was a 40-year-old woman with a genital lesion composed of a pedunculated nodule, a dome-shaped nodule and a subcutaneous nodule, measuring 5 cm in the greatest dimension. The largest, pedunculated nodule was histologically composed of an infundibulo-cystic structure with follicular, sebaceous and mesenchymal elements accompanied by cystic structures of various sizes lined by stratified squamous epithelium and follicular germinative cells suggesting follicular cysts. The dome-shaped nodule consisted of anastomosing strands of epithelial cells with follicular components. The subcutaneous nodule had two components, an infundibulo-cystic structure and a cyst lined by squamous epithelium. In our case, the unusual clinical feature of large and multiple nodules was due to the presence of several prominent hamartomatous cystic structures with FCH. This is the third case of giant FCH. The clinical presentation and location of giant FCH is unusual.

Original languageEnglish
Pages (from-to)191-195
Number of pages5
JournalJournal of Dermatology
Issue number3
Publication statusPublished - Mar 2006

All Science Journal Classification (ASJC) codes

  • Dermatology


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