A case of digital papillary adenocarcinoma

Naoko Wada, Hiroshi Uchi, Takamichi Ito, Hiromaro Kiryu, Masutaka Furue

Research output: Contribution to journalArticlepeer-review


We report a case of 50-year-old man who presented a digital tumor that had been gradually enlarging for 1 year. On examination, he had an ulcerated crusty nodule of 2 cm in diameter on his left thumb. Histopathologically, an excisional biopsy specimen showed infiltration of tumor cells with mitoses in the dermis and subcutis forming ductal structures. Immunohistochemically, these tumor cells were positive for AE1/AE3, EMA, and CK14, and focally positive for CEA, but were negative for estrogen receptor, progesterone receptor, and GCDFP15, with an MIB-1 index of 30%. He was diagnosed as having digital papillary adenocarcinoma and extended resection was carried out. Digital papillary adenocarcinoma is a malignant sweat gland tumor that frequently recurs and metastasizes. We described a clinically and histopathologically typical case of digital papillary adenocarcinoma.

Original languageEnglish
Pages (from-to)157-160
Number of pages4
JournalNishinihon Journal of Dermatology
Issue number2
Publication statusPublished - 2017

All Science Journal Classification (ASJC) codes

  • Dermatology


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