A case of alcoholic fibrosis with multiple nodular fatty infiltration in the liver

Kazufumi Dohmen; Kyoko Hidaka; Hirofumi Tanaka; Masatora Haruno; Yasunori Ichiki; Akihiro Nishie; Shinichi Aishima; Shinji Shimoda

doi:10.2957/kanzo.57.548

A case of alcoholic fibrosis with multiple nodular fatty infiltration in the liver

Kazufumi Dohmen, Kyoko Hidaka, Hirofumi Tanaka, Masatora Haruno, Yasunori Ichiki, Akihiro Nishie, Shinichi Aishima, Shinji Shimoda

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Abstract

A 48-year-old male was referred to our hospital due to symptoms of a general fatigue and anorexia. He was diagnosed to have liver dysfunction with elevated total bilirubin with 3.46 mg/dl, aspartate transaminase (AST) 384 IU/L and gamma-glutamyl transpeptidase (γ-GTP) 1067 IU/ml. Ultrasonography revealed multiple hyperechoic nodules in the liver. These nodules showed low density on computed tomography and high-intensity on T1-weighted and T2-weighted magnetic resonance imaging, which lost intensity with fat suppression technique. Histology obtained from the hyperechoic nodules in the liver showed macrovesicular steatosis. These nodules disappeared on CT three weeks after a conservative therapy, and liver biopsy at that time showed liver fibrosis.

Original language	English
Pages (from-to)	548-553
Number of pages	6
Journal	Acta Hepatologica Japonica
Volume	57
Issue number	10
DOIs	https://doi.org/10.2957/kanzo.57.548
Publication status	Published - 2016

All Science Journal Classification (ASJC) codes

Hepatology

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title = "A case of alcoholic fibrosis with multiple nodular fatty infiltration in the liver",

abstract = "A 48-year-old male was referred to our hospital due to symptoms of a general fatigue and anorexia. He was diagnosed to have liver dysfunction with elevated total bilirubin with 3.46 mg/dl, aspartate transaminase (AST) 384 IU/L and gamma-glutamyl transpeptidase (γ-GTP) 1067 IU/ml. Ultrasonography revealed multiple hyperechoic nodules in the liver. These nodules showed low density on computed tomography and high-intensity on T1-weighted and T2-weighted magnetic resonance imaging, which lost intensity with fat suppression technique. Histology obtained from the hyperechoic nodules in the liver showed macrovesicular steatosis. These nodules disappeared on CT three weeks after a conservative therapy, and liver biopsy at that time showed liver fibrosis.",

author = "Kazufumi Dohmen and Kyoko Hidaka and Hirofumi Tanaka and Masatora Haruno and Yasunori Ichiki and Akihiro Nishie and Shinichi Aishima and Shinji Shimoda",

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T1 - A case of alcoholic fibrosis with multiple nodular fatty infiltration in the liver

AU - Dohmen, Kazufumi

AU - Hidaka, Kyoko

AU - Tanaka, Hirofumi

AU - Haruno, Masatora

AU - Ichiki, Yasunori

AU - Nishie, Akihiro

AU - Aishima, Shinichi

AU - Shimoda, Shinji

PY - 2016

Y1 - 2016

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AB - A 48-year-old male was referred to our hospital due to symptoms of a general fatigue and anorexia. He was diagnosed to have liver dysfunction with elevated total bilirubin with 3.46 mg/dl, aspartate transaminase (AST) 384 IU/L and gamma-glutamyl transpeptidase (γ-GTP) 1067 IU/ml. Ultrasonography revealed multiple hyperechoic nodules in the liver. These nodules showed low density on computed tomography and high-intensity on T1-weighted and T2-weighted magnetic resonance imaging, which lost intensity with fat suppression technique. Histology obtained from the hyperechoic nodules in the liver showed macrovesicular steatosis. These nodules disappeared on CT three weeks after a conservative therapy, and liver biopsy at that time showed liver fibrosis.

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A case of alcoholic fibrosis with multiple nodular fatty infiltration in the liver

Abstract

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