A case of α-fetoprotein-producing gastric cancer showing an exogastric growth pattern

Hideaki Nakashima, Takashi Sakada, Makoto Otsuka, Yasuji Yoshikawa, Hiroaki Ueo, Masaki Mori, Tsuyoshi Akiyoshi

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4 Citations (Scopus)


A case of α-fetoprotein (AFP)-producing gastric cancer, which showed a huge abdominal mass due to an exogastric growth, is here described. A 69- year-old Japanese woman with a huge abdominal mass, measuring 22 x 15 cm in size, had a serum AFP level that was exceptionally high (155 x 103 ng/ml). CT, barium meal studies, and gastrointestinal fiberoscopy revealed a gastric tumor with an exogastric growth pattern. The patient underwent a partial gastrectomy. The histological examination revealed that the tumor consisted of anaplastic carcinoma with positive staining for AFP. Although no liver metastasis was observed at operation, she died of multiple liver metastases 8 weeks after the operation. A gastric cancer that shows both AFP production and an exogastric growth pattern is quite rare and may be virulent.

Original languageEnglish
Pages (from-to)150-153
Number of pages4
JournalJournal of Clinical Gastroenterology
Issue number2
Publication statusPublished - Mar 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Gastroenterology


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