TY - JOUR
T1 - A broadly applicable copper reagent for trifluoromethylations and perfluoroalkylations of aryl iodides and bromides
AU - Morimoto, Hiroyuki
AU - Tsubogo, Tetsu
AU - Litvinas, Nichole D.
AU - Hartwig, John F.
PY - 2011/4/11
Y1 - 2011/4/11
N2 - (Chemical Presented) Well compatible: The trifluoromethylations and perfluoroalkylations of aryl iodides and some aryl bromides with trifluoromethyl and perfluoroalkylcopper(I) phenanthroline complexes occur with broad scope at 25-50 8C (see scheme). The trifluoromethyl complex is prepared from inexpensive reagents and can be used in situ or isolated. The reactions tolerate a range of substituents and also occur with heteroaromatic systems.
AB - (Chemical Presented) Well compatible: The trifluoromethylations and perfluoroalkylations of aryl iodides and some aryl bromides with trifluoromethyl and perfluoroalkylcopper(I) phenanthroline complexes occur with broad scope at 25-50 8C (see scheme). The trifluoromethyl complex is prepared from inexpensive reagents and can be used in situ or isolated. The reactions tolerate a range of substituents and also occur with heteroaromatic systems.
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U2 - 10.1002/anie.201100633
DO - 10.1002/anie.201100633
M3 - Article
C2 - 21442711
AN - SCOPUS:79953675070
SN - 1433-7851
VL - 50
SP - 3793
EP - 3798
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 16
ER -