6-Amino-6-deoxychitosan. Preparation and application as plasmid vector in COS-1 cells

Taku Satoh; Takeshi Nagasaki; Nobuo Sakairi; Seiji Shinkai

doi:10.1246/cl.2004.340

6-Amino-6-deoxychitosan. Preparation and application as plasmid vector in COS-1 cells

Taku Satoh, Takeshi Nagasaki, Nobuo Sakairi, Seiji Shinkai

Institute for Advanced Study

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

6-Amino-6-deoxychitosan was prepared from 6-deoxy-6-halo-N- phthaloylchitosan via 6-azidation. The product has high stereoregularity because of the effective and regioselective reactions. To evaluate 6-amino-6- deoxychitosan as a gene transfer agent, transfection efficiencies of its complexes with plasmid DNA in COS-1 cells were examined.

Original language	English
Pages (from-to)	340-341
Number of pages	2
Journal	Chemistry Letters
Volume	33
Issue number	3
DOIs	https://doi.org/10.1246/cl.2004.340
Publication status	Published - Mar 2004

All Science Journal Classification (ASJC) codes

Chemistry(all)

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10.1246/cl.2004.340

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abstract = "6-Amino-6-deoxychitosan was prepared from 6-deoxy-6-halo-N- phthaloylchitosan via 6-azidation. The product has high stereoregularity because of the effective and regioselective reactions. To evaluate 6-amino-6- deoxychitosan as a gene transfer agent, transfection efficiencies of its complexes with plasmid DNA in COS-1 cells were examined.",

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AU - Satoh, Taku

AU - Nagasaki, Takeshi

AU - Sakairi, Nobuo

AU - Shinkai, Seiji

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Y1 - 2004/3

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AB - 6-Amino-6-deoxychitosan was prepared from 6-deoxy-6-halo-N- phthaloylchitosan via 6-azidation. The product has high stereoregularity because of the effective and regioselective reactions. To evaluate 6-amino-6- deoxychitosan as a gene transfer agent, transfection efficiencies of its complexes with plasmid DNA in COS-1 cells were examined.

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ER -

6-Amino-6-deoxychitosan. Preparation and application as plasmid vector in COS-1 cells

Abstract

All Science Journal Classification (ASJC) codes

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