2-(Heptylthio)pyrimidine-4,6-diamine

Gulrukh Salieva; Malokhat Uktamova; Kohei Torikai; Tursunali Kholikov

doi:10.3390/M1965

2-(Heptylthio)pyrimidine-4,6-diamine

Gulrukh Salieva
, Malokhat Uktamova
, Kohei Torikai
, Tursunali Kholikov

Inorganic and Analytical Chemistry

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Thiopyrimidines represent one of the most active classes of compounds, possessing a wide spectrum of biological activities. Herein, we report the synthesis of 2-(heptylthio)pyrimidine-4,6-diamine (HPDA) via S-alkylation. The structure of HPDA was elucidated using ¹H and ¹³C nuclear magnetic resonance (NMR), heteronuclear multiple bond correlation (HMBC), high resolution mass (HRMS), and infrared (IR) spectroscopies.

Original language	French
Article number	M1965
Journal	MolBank
Volume	2025
Issue number	1
DOIs	https://doi.org/10.3390/M1965
Publication status	Published - Mar 2025

All Science Journal Classification (ASJC) codes

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Access to Document

10.3390/M1965

Cite this

@article{5f0ff5eb7c8b4372a343c2d8fad0581a,

title = "2-(Heptylthio)pyrimidine-4,6-diamine",

abstract = "Thiopyrimidines represent one of the most active classes of compounds, possessing a wide spectrum of biological activities. Herein, we report the synthesis of 2-(heptylthio)pyrimidine-4,6-diamine (HPDA) via S-alkylation. The structure of HPDA was elucidated using 1H and 13C nuclear magnetic resonance (NMR), heteronuclear multiple bond correlation (HMBC), high resolution mass (HRMS), and infrared (IR) spectroscopies.",

keywords = "4,6-diamino-2-mercaptopyrimidine, S-alkylation, alkylation",

author = "Gulrukh Salieva and Malokhat Uktamova and Kohei Torikai and Tursunali Kholikov",

note = "Publisher Copyright: {\textcopyright} 2025 by the authors.",

year = "2025",

month = mar,

doi = "10.3390/M1965",

language = "フランス語",

volume = "2025",

journal = "MolBank",

issn = "1422-8599",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "1",

}

TY - JOUR

T1 - 2-(Heptylthio)pyrimidine-4,6-diamine

AU - Salieva, Gulrukh

AU - Uktamova, Malokhat

AU - Torikai, Kohei

AU - Kholikov, Tursunali

PY - 2025/3

Y1 - 2025/3

N2 - Thiopyrimidines represent one of the most active classes of compounds, possessing a wide spectrum of biological activities. Herein, we report the synthesis of 2-(heptylthio)pyrimidine-4,6-diamine (HPDA) via S-alkylation. The structure of HPDA was elucidated using 1H and 13C nuclear magnetic resonance (NMR), heteronuclear multiple bond correlation (HMBC), high resolution mass (HRMS), and infrared (IR) spectroscopies.

AB - Thiopyrimidines represent one of the most active classes of compounds, possessing a wide spectrum of biological activities. Herein, we report the synthesis of 2-(heptylthio)pyrimidine-4,6-diamine (HPDA) via S-alkylation. The structure of HPDA was elucidated using 1H and 13C nuclear magnetic resonance (NMR), heteronuclear multiple bond correlation (HMBC), high resolution mass (HRMS), and infrared (IR) spectroscopies.

KW - 4,6-diamino-2-mercaptopyrimidine

KW - S-alkylation

KW - alkylation

UR - https://www.scopus.com/pages/publications/105001247287

UR - https://www.scopus.com/pages/publications/105001247287#tab=citedBy

U2 - 10.3390/M1965

DO - 10.3390/M1965

M3 - 学術誌

AN - SCOPUS:105001247287

SN - 1422-8599

VL - 2025

JO - MolBank

JF - MolBank

IS - 1

M1 - M1965

ER -

2-(Heptylthio)pyrimidine-4,6-diamine

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Cite this