17,20β,21-Trihydroxy-4-pregnen-3-one

Yukiko Ogino; Shinichi Miyagawa; Taisen Iguchi

doi:10.1016/B978-0-12-801028-0.00222-1

17,20β,21-Trihydroxy-4-pregnen-3-one

Yukiko Ogino, Shinichi Miyagawa, Taisen Iguchi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Citations (Scopus)

Abstract

17,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DP) and 17,20β,21-Trihydroxy-4-pregnen-3-one (20β-S) are identified as maturation inducing steroids in teleost fish. 20β-S is produced from 11-deoxycortisol by 20β-hydroxysteroid dehydrogenase (20β-HSD) in ovarian follicular cells under the influence of pituitary gonadotropin. It stimulates the meiotic maturation of oocytes during GVBD. Biological actions of these steroids are mediated by both membrane and nuclear receptors.

Original language	English
Title of host publication	Handbook of Hormones
Subtitle of host publication	Comparative Endocrinology for Basic and Clinical Research
Publisher	Elsevier
Pages	511-512
Number of pages	2
ISBN (Electronic)	9780128010280
ISBN (Print)	9780128010679
DOIs	https://doi.org/10.1016/B978-0-12-801028-0.00222-1
Publication status	Published - Jan 1 2015
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Medicine

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10.1016/B978-0-12-801028-0.00222-1

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title = "17,20β,21-Trihydroxy-4-pregnen-3-one",

abstract = "17,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DP) and 17,20β,21-Trihydroxy-4-pregnen-3-one (20β-S) are identified as maturation inducing steroids in teleost fish. 20β-S is produced from 11-deoxycortisol by 20β-hydroxysteroid dehydrogenase (20β-HSD) in ovarian follicular cells under the influence of pituitary gonadotropin. It stimulates the meiotic maturation of oocytes during GVBD. Biological actions of these steroids are mediated by both membrane and nuclear receptors.",

author = "Yukiko Ogino and Shinichi Miyagawa and Taisen Iguchi",

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T1 - 17,20β,21-Trihydroxy-4-pregnen-3-one

AU - Ogino, Yukiko

AU - Miyagawa, Shinichi

AU - Iguchi, Taisen

PY - 2015/1/1

Y1 - 2015/1/1

N2 - 17,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DP) and 17,20β,21-Trihydroxy-4-pregnen-3-one (20β-S) are identified as maturation inducing steroids in teleost fish. 20β-S is produced from 11-deoxycortisol by 20β-hydroxysteroid dehydrogenase (20β-HSD) in ovarian follicular cells under the influence of pituitary gonadotropin. It stimulates the meiotic maturation of oocytes during GVBD. Biological actions of these steroids are mediated by both membrane and nuclear receptors.

AB - 17,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DP) and 17,20β,21-Trihydroxy-4-pregnen-3-one (20β-S) are identified as maturation inducing steroids in teleost fish. 20β-S is produced from 11-deoxycortisol by 20β-hydroxysteroid dehydrogenase (20β-HSD) in ovarian follicular cells under the influence of pituitary gonadotropin. It stimulates the meiotic maturation of oocytes during GVBD. Biological actions of these steroids are mediated by both membrane and nuclear receptors.

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DO - 10.1016/B978-0-12-801028-0.00222-1

M3 - Chapter

AN - SCOPUS:85146401351

SN - 9780128010679

SP - 511

EP - 512

BT - Handbook of Hormones

PB - Elsevier

ER -

17,20β,21-Trihydroxy-4-pregnen-3-one

Abstract

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