17, 20β-Dihydroxy-4-pregnen-3-one (17α, 20β-DP) and 17, 20β, 21-Trihydroxy-4-pregnen-3-one (20β-S) are identified as maturation-inducing steroids in teleost fish. 20β-S is produced from 11-deoxycortisol by 20β-hydroxysteroid dehydrogenase (20β-HSD) in ovarian follicular cells under the influence of pituitary gonadotropin. It stimulates the meiotic maturation of oocytes during GVBD. The biological actions of these steroids are mediated by both membrane and nuclear receptors.
|Title of host publication||Handbook of Hormones|
|Subtitle of host publication||Comparative Endocrinology for Basic and Clinical Research|
|Number of pages||2|
|Publication status||Published - Jan 1 2021|
All Science Journal Classification (ASJC) codes