糖尿病自然発症ラットを用いた紫カンショ発酵紅酢の糖尿病前症段階からの予防ポテンシャル

Kazuhiro Takao; Naoki Morishita; Norihiko Terahara; Keiichi Fukui; Toshiro Matsui

doi:10.3136/nskkk.65.552

糖尿病自然発症ラットを用いた紫カンショ発酵紅酢の糖尿病前症段階からの予防ポテンシャル

Translated title of the contribution: Anti-diabetic Effect of Acetic Acid-Free Red Vinegar in Spontaneously Diabetic Torii Rats

Kazuhiro Takao, Naoki Morishita, Norihiko Terahara, Keiichi Fukui, Toshiro Matsui

Food Science and Biotechnology

Research output: Contribution to journal › Article › peer-review

Abstract

The aim of this study was to evaluate the anti-diabetic potential of acetic acid-free red vinegar (RV) containing a candidate, 6-O-caffeoylsophorose (CS), in spontaneously diabetic Torii (SDT) rats. In accordance with administration protocols, ingestion by SDT began between the ages of 11 and 16 weeks which corresponded to normal and prediabetic stages, respectively. Daily intake of RV (4.3 mg/kg/day) led to a significant reduction in fasting blood glucose level (BGL) in 28-wk SDT (fasting BGL: control, 133.8±12.8 mg/mL; RV, 98.5±19.8 mg/mL), while no anti-diabetic effect was obtained in SDT fed from 27 weeks of age. These results demonstrated that RV has physiological potential to suppress promotion of diabetes, but not to improve the developed of onset.

Translated title of the contribution	Anti-diabetic Effect of Acetic Acid-Free Red Vinegar in Spontaneously Diabetic Torii Rats
Original language	Japanese
Pages (from-to)	552-558
Number of pages	7
Journal	Nippon Shokuhin Kagaku Kogaku Kaishi
Volume	65
Issue number	12
DOIs	https://doi.org/10.3136/nskkk.65.552
Publication status	Published - 2018

All Science Journal Classification (ASJC) codes

Food Science

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3136/nskkk.65.552

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title = "糖尿病自然発症ラットを用いた紫カンショ発酵紅酢の糖尿病前症段階からの予防ポテンシャル",

abstract = "The aim of this study was to evaluate the anti-diabetic potential of acetic acid-free red vinegar (RV) containing a candidate, 6-O-caffeoylsophorose (CS), in spontaneously diabetic Torii (SDT) rats. In accordance with administration protocols, ingestion by SDT began between the ages of 11 and 16 weeks which corresponded to normal and prediabetic stages, respectively. Daily intake of RV (4.3 mg/kg/day) led to a significant reduction in fasting blood glucose level (BGL) in 28-wk SDT (fasting BGL: control, 133.8±12.8 mg/mL; RV, 98.5±19.8 mg/mL), while no anti-diabetic effect was obtained in SDT fed from 27 weeks of age. These results demonstrated that RV has physiological potential to suppress promotion of diabetes, but not to improve the developed of onset.",

author = "Kazuhiro Takao and Naoki Morishita and Norihiko Terahara and Keiichi Fukui and Toshiro Matsui",

note = "Publisher Copyright: Copyright{\textcopyright} 2018, Japanese Society for Food Science and Technology",

year = "2018",

doi = "10.3136/nskkk.65.552",

language = "日本語",

volume = "65",

pages = "552--558",

journal = "Nippon Shokuhin Kagaku Kogaku Kaishi",

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publisher = "Japanese Society for Food Science and Technology",

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T1 - 糖尿病自然発症ラットを用いた紫カンショ発酵紅酢の糖尿病前症段階からの予防ポテンシャル

AU - Takao, Kazuhiro

AU - Morishita, Naoki

AU - Terahara, Norihiko

AU - Fukui, Keiichi

AU - Matsui, Toshiro

PY - 2018

Y1 - 2018

N2 - The aim of this study was to evaluate the anti-diabetic potential of acetic acid-free red vinegar (RV) containing a candidate, 6-O-caffeoylsophorose (CS), in spontaneously diabetic Torii (SDT) rats. In accordance with administration protocols, ingestion by SDT began between the ages of 11 and 16 weeks which corresponded to normal and prediabetic stages, respectively. Daily intake of RV (4.3 mg/kg/day) led to a significant reduction in fasting blood glucose level (BGL) in 28-wk SDT (fasting BGL: control, 133.8±12.8 mg/mL; RV, 98.5±19.8 mg/mL), while no anti-diabetic effect was obtained in SDT fed from 27 weeks of age. These results demonstrated that RV has physiological potential to suppress promotion of diabetes, but not to improve the developed of onset.

AB - The aim of this study was to evaluate the anti-diabetic potential of acetic acid-free red vinegar (RV) containing a candidate, 6-O-caffeoylsophorose (CS), in spontaneously diabetic Torii (SDT) rats. In accordance with administration protocols, ingestion by SDT began between the ages of 11 and 16 weeks which corresponded to normal and prediabetic stages, respectively. Daily intake of RV (4.3 mg/kg/day) led to a significant reduction in fasting blood glucose level (BGL) in 28-wk SDT (fasting BGL: control, 133.8±12.8 mg/mL; RV, 98.5±19.8 mg/mL), while no anti-diabetic effect was obtained in SDT fed from 27 weeks of age. These results demonstrated that RV has physiological potential to suppress promotion of diabetes, but not to improve the developed of onset.

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DO - 10.3136/nskkk.65.552

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JO - Nippon Shokuhin Kagaku Kogaku Kaishi

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ER -

糖尿病自然発症ラットを用いた紫カンショ発酵紅酢の糖尿病前症段階からの予防ポテンシャル

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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