(η6-arene)RuII/chiral SN ligand: A novel bifunctional catalyst system for asymmetric transfer hydrogenation of aromatic ketones

Masato Ito; Yuji Shibata; Akira Watanabe; Takao Ikariya

doi:10.1055/s-0029-1217349

(η6-arene)Ru^II/chiral SN ligand: A novel bifunctional catalyst system for asymmetric transfer hydrogenation of aromatic ketones

Masato Ito, Yuji Shibata, Akira Watanabe, Takao Ikariya

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

A binary catalyst system of [RuCl₂(η⁶-arene)] ₂ and a protic aminothiol (SN) ligand has been found to promote hydrogen transfer between alcohols and carbonyl compounds. The chiral catalyst system with the pipecolinol-derived chiral SN ligand displays excellent stereoselectivity in the asymmetric transfer hydrogenation of aromatic ketones using HCO₂H-Et₃N. Novel unsymmetrical bis(thiolate)- bridged binuclear complex, which is relevant to the generation of catalytically active species, has been synthesized and structurally characterized.

Original language	English
Pages (from-to)	1621-1626
Number of pages	6
Journal	Synlett
Issue number	10
DOIs	https://doi.org/10.1055/s-0029-1217349
Publication status	Published - Jun 2009
Externally published	Yes

All Science Journal Classification (ASJC) codes

Organic Chemistry

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abstract = "A binary catalyst system of [RuCl2(η6-arene)] 2 and a protic aminothiol (SN) ligand has been found to promote hydrogen transfer between alcohols and carbonyl compounds. The chiral catalyst system with the pipecolinol-derived chiral SN ligand displays excellent stereoselectivity in the asymmetric transfer hydrogenation of aromatic ketones using HCO2H-Et3N. Novel unsymmetrical bis(thiolate)- bridged binuclear complex, which is relevant to the generation of catalytically active species, has been synthesized and structurally characterized.",

author = "Masato Ito and Yuji Shibata and Akira Watanabe and Takao Ikariya",

year = "2009",

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AU - Shibata, Yuji

AU - Watanabe, Akira

AU - Ikariya, Takao

PY - 2009/6

Y1 - 2009/6

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AB - A binary catalyst system of [RuCl2(η6-arene)] 2 and a protic aminothiol (SN) ligand has been found to promote hydrogen transfer between alcohols and carbonyl compounds. The chiral catalyst system with the pipecolinol-derived chiral SN ligand displays excellent stereoselectivity in the asymmetric transfer hydrogenation of aromatic ketones using HCO2H-Et3N. Novel unsymmetrical bis(thiolate)- bridged binuclear complex, which is relevant to the generation of catalytically active species, has been synthesized and structurally characterized.

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JF - Synlett

IS - 10

ER -

(η6-arene)Ru^II/chiral SN ligand: A novel bifunctional catalyst system for asymmetric transfer hydrogenation of aromatic ketones

Abstract

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