ζ-COP, a subunit of coatomer, is required for COP-coated vesicle assembly

Osamu Kuge; Sayuri Hara-Kuge; Lelio Orci; Mariella Ravazzola; Mylene Amherdt; Gary Tanigawa; Felix T. Wieland; James E. Rothman

ζ-COP, a subunit of coatomer, is required for COP-coated vesicle assembly

Osamu Kuge
, Sayuri Hara-Kuge
, Lelio Orci
, Mariella Ravazzola
, Mylene Amherdt
, Gary Tanigawa
, Felix T. Wieland
, James E. Rothman

Research output: Contribution to journal › Article › peer-review

Abstract

cDNA encoding the 20-kD subunit of coatomer, ζ-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to ζ-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP-coated vesicles on Golgi cisternae. Unlike other coatomer subunits (β-, β′-, γ-, and ∈-COP), ζ-COP exists in both coatomer bound and free pools.

Original language	English
Pages (from-to)	1727-1734
Number of pages	8
Journal	Journal of Cell Biology
Volume	123
Issue number	6 PART 2
Publication status	Published - Dec 1993
Externally published	Yes

All Science Journal Classification (ASJC) codes

Cell Biology

Cite this

@article{f28ca2578d194edea303db2910c561e9,

title = "ζ-COP, a subunit of coatomer, is required for COP-coated vesicle assembly",

abstract = "cDNA encoding the 20-kD subunit of coatomer, ζ-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to ζ-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP-coated vesicles on Golgi cisternae. Unlike other coatomer subunits (β-, β′-, γ-, and ∈-COP), ζ-COP exists in both coatomer bound and free pools.",

author = "Osamu Kuge and Sayuri Hara-Kuge and Lelio Orci and Mariella Ravazzola and Mylene Amherdt and Gary Tanigawa and Wieland, \{Felix T.\} and Rothman, \{James E.\}",

year = "1993",

month = dec,

language = "English",

volume = "123",

pages = "1727--1734",

journal = "Journal of Cell Biology",

issn = "0021-9525",

publisher = "Rockefeller University Press",

number = "6 PART 2",

}

TY - JOUR

T1 - ζ-COP, a subunit of coatomer, is required for COP-coated vesicle assembly

AU - Kuge, Osamu

AU - Hara-Kuge, Sayuri

AU - Orci, Lelio

AU - Ravazzola, Mariella

AU - Amherdt, Mylene

AU - Tanigawa, Gary

AU - Wieland, Felix T.

AU - Rothman, James E.

PY - 1993/12

Y1 - 1993/12

N2 - cDNA encoding the 20-kD subunit of coatomer, ζ-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to ζ-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP-coated vesicles on Golgi cisternae. Unlike other coatomer subunits (β-, β′-, γ-, and ∈-COP), ζ-COP exists in both coatomer bound and free pools.

AB - cDNA encoding the 20-kD subunit of coatomer, ζ-COP, predicts a protein of 177-amino acid residues, similar in sequence to AP17 and AP19, subunits of the clathrin adaptor complexes. Polyclonal antibody directed to ζ-COP blocks the binding of coatomer to Golgi membranes and prevents the assembly of COP-coated vesicles on Golgi cisternae. Unlike other coatomer subunits (β-, β′-, γ-, and ∈-COP), ζ-COP exists in both coatomer bound and free pools.

UR - https://www.scopus.com/pages/publications/0027752244

UR - https://www.scopus.com/pages/publications/0027752244#tab=citedBy

M3 - Article

C2 - 8276893

AN - SCOPUS:0027752244

SN - 0021-9525

VL - 123

SP - 1727

EP - 1734

JO - Journal of Cell Biology

JF - Journal of Cell Biology

IS - 6 PART 2

ER -

ζ-COP, a subunit of coatomer, is required for COP-coated vesicle assembly

Abstract

All Science Journal Classification (ASJC) codes

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